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Overview
BCH 190
Issues in Biotechnology, BCH
190, is intended for a broad audience; including, undergraduate students,
Life Science industry staff, high school teachers and high school students
for college credit regardless of their major or degree program.
There are no prerequisites. This course aims to accomplish three goals:
1) Provide basic knowledge about DNA, genomics and gene expression that
is fundamental to the how biological life functions
2) Present a panoramic survey of the current applications in biotechnology,
and career opportunities in the growing fields that are related to biotechnology
3) Examine issues and ethics concerning the future of biotechnology and
our society.
This course can be taken for (3) college credits through the University
of Rhode Island.
Accreditation through the University of Rhode Island is transferable to
most programs.
The entire course is available as a 42 DVD series in a digital textbook
streamed through the lifeedu.org website that spans the fields of biotechnology.
This format allows for students to take this course on their own schedule
from any location.
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An Introduction
Education about biology and biotechnology has become imperative. What
we know now about the biological sciences and their applications in biotechnology
will affect all of us and shape many facets of our global society well
into the future. There is not a more profound, provocative, and socially
relevant topic for education currently.
How does life work? What is life? How are genes sequenced or cloned? Should
we be cloning genes and moving them into other organisms? How will biotechnology
affect medicine, pharmacy, and agriculture? Should we be cloning and genetically
engineering animals? Should the federal government support stem cell research?
What are the ethical issues? What are the career opportunities in the
various fields that utilize biotech? These are currently just some of
the important and socially relevant questions regarding the extraordinary
advances in biotechnology that are addressed in this new course titled
“The Way We Work With Life: Issues in Biotechnology”.Knowledge
about how life on this planet works should be a part of basic education
and will provide a basis for informed dialogue about the current advances
in all of the various and often controversial fields of biotechnology.
Course Description
The biological and environmental sciences have been rapidly transformed
by the introduction of DNA-based technologies that allow for the precise
manipulation and examination of the genetic material of plants, animals
and microbes. The applications of these technologies encompass the rapidly
growing fields within biotechnology. The tools of biotechnology are currently
being applied across the biological sciences to address problems in agricultural
crop improvement, marine sciences and aquaculture, medicine, pharmacy,
forensics, and public health. The introduction of this field has been
extremely rapid and has created a tremendous educational need to keep
pace.
This course provides an introduction to Biotechnology and its impact on
the environmental and life sciences, medicine, and agriculture. First,
the basic questions concerning What is Life? and How does it work? are
examined. To address these questions, the fundamental mechanics of biological
life, DNA, gene expression and cloning are presented in basic layman’s
terms as a basis for the current applications of modern biotechnology.
Next, the current basic techniques used for gene cloning, DNA sequencing,
PCR and gene transfer are examined. These technologies provide the basis
for biotechnological advances in medical, pharmaceutical, agricultural,
environmental, and forensic applications. Applications of recombinant
DNA and genetic engineering are explored in these areas that are dramatically
affecting our society and future. Lastly, the implications of biotechnology
to world economy, politics, ecology and ethics are also discussed.
1. Background
Today, the term ‘biotechnology’ most frequently refers to
the use of DNA-based technologies that are now so widely used in medical,
pharmaceutical, agricultural, environmental, and forensic applications.
News and breakthroughs in biotechnology are now common in the popular
press. For example, a recent special issue of TIME magazine was titled
“Biotechnology-The future is now”. However, education of the
public is lagging significantly behind the rate of advancement in this
rapidly developing field.
The techniques to clone the first gene were developed more that thirty
years ago. Now it is possible to clone genes from any organism, including
bacteria, fungi, plants and animals and transfer those cloned genes into
other organisms. For example, a gene can be cloned from a bacterium, and
moved into a plant such as corn where the plant will then make the protein
that is usually made by the bacteria. The transferred DNA sequence, or
transgene, directs the cell to make its specific protein product and provides
the potential for new traits.Given the rapid recent advances in genomics,
transgenic biology, stem cell research and other related areas of biotechnology
and a prediction that these fields will continue to grow and become increasing
more sophisticated, there is an increasing need to create an informed
and educated public in this area. The fact that there are various concerns
and issues regarding the various fields of biotechnology further underscores
the need for increased public education and awareness.
Educational Objectives for BCH 190:
This course, Issues in Biotechnology (BCH 190), is intended for the general
public, Life Science Industry staff, high school teachers and undergraduate
students regardless of their major or degree program. It also forms the
basis for the graduate level versions of this course. There are no prerequisites.
The course aims to accomplish three goals: 1) to provide basic knowledge
about DNA and gene expression that is fundamental to the how biological
life functions, 2) to present the current applications in biotechnology,
and career opportunities in the growing fields that are related to biotechnology;
and 3) to examine issues and ethics concerning the future of biotechnology
and our society. This course provides a perspective on the rapidly changing
fields of biotechnology and offers insight into careers.
Texts
Exploring The Way Life Works. The Science of Biology. Hoagland, Mahlon
& Dodson, Bert ed. Hauck, Judith. 2001. Jones and Bartlett Publishers,
Inc. Sudbury MA
Available from www.lifeedu.org under the heading “Resources”
as well as the URI book store.
Additional readings as assigned.
Student Workbook of Lectures in the series $65.00 (optional)
must be ordered at iCopy 99 Fortin Road, Kingston RI 02881 tele 401-788-8277
Quizzes
Quizzes will be given after each assignment via online testing through
the lifeedu website. The tests and quizzes will cover: the weekly assigned
chapter from the class text (The Way Life Works) focusing on both concepts
and vocabulary, from that weeks class lecture and assigned reading from
the previous class. These quizzes consist of 20 multiple choice questions
and should be a test of your general knowledge on the subject.
3 Exams will be given at the end of each module and will cover both class
lecture material as well as the class text. The final exam is comprehensive.
Stock Project each student will be responsible for a project, due before
the end of term, detailing current market analysis of several publicly
traded biotechnology companies. This project will be summarized with a
written report and survey.
TUITION COSTS: ON-LINE
PRESENTATION
• SCIENCE, NON-SCIENCE STAFF AND UNDERGRADUATES ($1012)
• HIGH SCHOOL SENIORS ($195) (Special rates)
• HIGH AND MIDDLE SCHOOL TEACHERS ($1012)
A
General Syllabus
The Way We Work With Life |
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Modular Lecture Series |
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I. The Mechanics of Life: What is Life? |
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Issues in Biotechnology: Panacea or Pandora's Box |
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The Way Life Works. Setting the Stage and The Patterns
of Life. Open Forum Discussion |
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Energy from Light to Life & The Information
of Life |
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The Mechanics of Life & Feedback Loops |
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The Unity and Community of Life & Evolution
as a Pattern |
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The Techniques and Applications of DNA-based biotechnology |
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II. Applications of Biotechnology: The future
is now |
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Agricultural Biotechnology I |
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Agricultural Biotechnology II:GMO Foods: Risks
and Benefits |
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Medical Biotechnology: Gene therapy, … |
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Stem cells: The Controversy and the Reality |
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Biotechnology and Pharmaceuticals |
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The Genomics Revolution and Pharmacogenomics |
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Animal cloning and Genetic Engineering |
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Marine Biotechnology |
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Environmental Biotechnology |
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Careers, Job Compensation and Gender in Biotechnology |
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DNA and Forensics |
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Forensic DNA based Biotechnology |
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Genetics and Public Health |
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Bioweapons and Counter Defense |
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III. Biotechnology: Ethical Issues and Concerns |
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Biotechnology: Ethical Issues and Concerns: an
overview |
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Genomics and informed consent: Diagnosing secrets
and the right to know |
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Human therapeutic and reproductive cloning |
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Future Perspectives: Should We and Who decides |
Globalization
and Biotechnology |
Freedom of Choice |
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Other topics of interest |
| Biotechnology and Current Investments |
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Patents and Regulatory Affairs |
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Biotechnology, Religions and Modern Philosophy
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Organic Farming, Conventional Agriculture and Biotechnology |
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